Contact us for Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes
Paraoxonase-1 (PON1) is a high-density lipoprotein-associated esterase and is speculated to play a role in several human diseases including diabetes mellitus and atherosclerosis. A low PON1 function has been linked with an increased likelihood of major heart attacks, and numerous research studies are being conducted to assess the cardioprotective effects and clinical value of PON1. The primary goal of this research was to identify the most important studies and then determine whether PON1 is of clinical significance. A literature review found that no evidence suggests that PON1 has clinical significance. Our opinion is that rigorous research is required to determine the clinical significance of PON1. Learn more here.
Paraoxonase-1 in human serum (PON1) is a calcium-dependent enzyme for hydrolysis that is present in a wide variety of mammals. Abraham Mazur and Norman Aldridge were pivotal in the discovery and classifying PON1 during the late 1940s and into the mid-1950s. The enzymes at first were identified as "A"-esterases however, they later came to be all-encompassingly known as paraoxonases due to their capacity to degrade the organophosphate compound, paraoxon, which is the toxic compound for parathion which is an extensively used insecticide in agriculture. Don't hesitate to knock us for Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes. Immunetics is the most reputed company for these KITS AND REAGENTS in Cambridge, MA. For more details, visit us through our website. Learn more about Are you looking for Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes?
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